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I-90 – Major east-west interstate running across the state from the Ohio border through Buffalo, Rochester, Syracuse, and Albany toward Massachusetts.
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I-87 – Runs north–south from New York City up the Hudson Valley to the Canadian border.
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I-95 – Follows the eastern edge near New York City and Long Island, connecting to New Jersey and Connecticut.
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I-78 – Connects New York City’s Holland Tunnel with Pennsylvania.
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U.S. Highways and State Routes interconnect smaller cities and rural areas and link to the vast Amtrak rail system, ferries (such as those serving Staten Island and Long Island), and major airports like JFK, LaGuardia, and Albany International.